The Artemis II astronauts are bound for Earth after conducting a historic lunar fly-by and witnessing a total solar eclipse from their spacecraft.
Commander Reid Wiseman says the Orion spacecraft crew "saw sights that no human has ever seen", while pilot Victor Glover says there are "no adjectives" to describe what they observed, BBC reports.
The spacecraft reached its maximum distance from Earth - 252,756 miles (406,771km) - during the lunar fly-by. The crew had already broken the previous record for the furthest distance humans have travelled into space.
The astronauts lost connection with Nasa while behind the Moon - the outage was expected and lasted around 40 minutes.
"It is so great to hear from Earth again," said mission specialist Christina Koch as she broke the silence from the spacecraft.
US President Donald Trump tells the astronauts that they have "made history and made all America really proud" - and invites them to the White House.
Orion didn't land on the Moon's surface, but looped around its far side and back again.
