Canadian police on Monday said that ten people had been killed and at least 15 others injured in two remote communities in Saskatchewan.
The Royal Canadian Mounted Police (RCMP) have launched a manhunt for two suspects in one of the nation's deadliest incidents of mass violence.
RCMP Assistant Commissioner Rhonda Blackmore told a news conference that officers had found 10 people dead in 13 locations in the community of James Smith Cree Nation and the nearby town of Weldon, in Canada's Saskatchewan province.
"It is horrific what has occurred in our province today," she said. "We are actively looking for the two suspects."
Blackmore said it was still to early to glean the attacker's motive, because "some of the victims were targeted by the suspects and others were attacked randomly."
"To speak to a motive would be extremely difficult at this point in time," she said.
Blackmore said at least 15 other people had been transported to hospital.
The James Smith First Nation is an indigenous community with about 3,400 inhabitants mainly engaged in agriculture, hunting and fishing. Weldon is a village with about 200 inhabitants.
The community declared a local state of emergency, while many Saskatchewan residents were urged to seek shelter locally.
Canadian Prime Minister Justin Trudeau called the mass stabbing "horrific and heartbreaking." "I'm thinking of those who have lost a loved one and of those who were injured," he tweeted.
Police launched a manhunt for two suspects. They named Damien S. and Myles S. as the two suspects and said the pair were driving a black Nissan Rogue.
Multiple checkpoints have been set up on highways and roads across the region as "maximum" police resources have been deployed to search for the suspects, Blackmore said.
Police bulletins urged to report any suspicious people and to take precautions like staying at home. An advisory also warned against picking up hitchhikers or approaching suspicious people.
Following reported sightings of the suspects in Regina, the provincial capital more than 300 kilometers (185 miles) south, the alert and search has been extended to neighboring provinces of Manitoba and Alberta.